Article
Efficacy of genotype-matched vaccine against re-emerging genotype V Japanese encephalitis virus.
Emerging microbes & infections - 1 Dec 2024
Kim Jae-Deog, Lee Ah-Ra, Moon Dah-Hyun, Chung Young-Uk, Hong Su-Yeon, Cho Hyo Je, Kang Tae Hyun, Jang Yo Han, Sohn Myung Hyun, Seong Baik-Lin, Seo Sang-Uk
Abstract excerpt
Japanese encephalitis (JE), caused by the Japanese encephalitis virus (JEV), is a highly threatening disease with no specific treatment. Fortunately, the development of vaccines has enabled effective defense against JE. However, re-emerging genotype V (GV) JEV poses a challenge as current vaccines are genotype III (GIII)-based and provide suboptimal protection. Given the isolation of GV JEVs from Malaysia, China,...
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