Article
Japanese encephalitis virus vaccine candidates generated by chimerization with dengue virus type 4.
Vaccine - 23 May 2014
Gromowski Gregory D, Firestone Cai-Yen, Hanson Christopher T, Whitehead Stephen S
Abstract excerpt
Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis worldwide and vaccination is one of the most effective ways to prevent disease. A suitable live-attenuated JEV vaccine could be formulated with a live-attenuated tetravalent dengue vaccine for the control of these viruses in endemic areas. Toward this goal, we generated chimeric virus vaccine candidates by replacing the precursor membrane...
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