Article
Genotype-specific neutralization determinants in envelope protein: implications for the improvement of Japanese encephalitis vaccine.
The Journal of general virology - 1 Aug 2015
Ye Qing, Xu Yan-Peng, Zhang Yu, Li Xiao-Feng, Wang Hong-Jiang, Liu Zhong-Yu, Li Shi-Hua, Liu Long, Zhao Hui, Nian Qing-Gong, Deng Yong-Qiang, Qin E-De, Qin Cheng-Feng
Abstract excerpt
Japanese encephalitis remains the leading cause of viral encephalitis in children in Asia and is expanding its geographical range to larger areas in Asia and Australasia. Five genotypes of Japanese encephalitis virus (JEV) co-circulate in the geographically affected areas. In particular, the emergence of genotype I (GI) JEV has displaced genotype III (GIII) as the dominant circulating genotype in many Asian...
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