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Article

Different Kynurenine Pathway Dysregulation in Systemic Sclerosis in Men and Women

29 Mar 2024

Abstract excerpt

Systemic sclerosis (SSc), a predominantly female-affected systemic autoimmune disease, requires tailored treatment strategies contingent on organ involvement and symptom severity. Given SSc's inflammatory nature, the involvement of the kynurenine pathway (KP) in its pathophysiology is underexplored. Our study aimed to investigate sex-related differences in KP activation among SSc patients and assess the impact of...

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PMID: 38612652
DOI: 10.3390/ijms25073842

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