Article

Kynurenic acid underlies sex-specific immune responses to COVID-19

2020-09-08

Abstract excerpt

Coronavirus disease-2019 (COVID-19) has poorer clinical outcomes in males compared to females, and immune responses underlie these sex-related differences in disease trajectory. As immune responses are in part regulated by metabolites, we examined whether the serum metabolome has sex-specificity for immune responses in COVID-19. In males with COVID-19, kynurenic acid (KA) and a high KA to kynurenine (K) ratio was...

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Literature Corpus work: 4cd3f458-3c51-50ff-a75c-d84adbb73f75
DOI: 10.1101/2020.09.06.20189159

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