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Pregnancy complications affect kynurenine pathway metabolite concentrations in umbilical cord blood

21 Jul 2025

Abstract excerpt

BACKGROUND: Tryptophan and its kynurenine pathway (KP) metabolites play key roles in modulating the immune system and vasculature, and exhibit both pro- and antioxidant properties, making them crucial for a healthy pregnancy and fetal development. Disruptions in the KP may impact both prenatal and postnatal health, however, data on fetal KP metabolite concentrations and their alterations in pregnancy-related...

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PMID: 40691607
DOI: 10.1186/s12958-025-01436-6

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