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The Kynurenine Pathway in Stem Cell Biology

1 Jan 2013

Abstract excerpt

The kynurenine pathway (KP) is the main catabolic pathway of the essential amino acid tryptophan. The KP has been identified to play a critical role in regulating immune responses in a variety of experimental settings. It is also known to be involved in several neuroinflammatory diseases including Huntington's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. This review considers the current...

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PMID: 24092986
DOI: 10.4137/ijtr.s12626

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