Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex Bias in Systemic Sclerosis: from Clinical to Immunological Differences

27 May 2025

Abstract excerpt

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microvasculopathy, extensive fibrosis, and autoantibodies. The disease affects mostly the female sex. In this review, we highlight sex bias in clinical manifestations in SSc, and the pathophysiological changes underlying this bias. Male sex is associated with the diffuse cutaneous form of the disease, digital ulcers, interstitial lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Disorders and Syndromes
Share to Mast cells and histamine
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40423726
DOI: 10.1007/s12016-025-09062-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex Bias in Systemic Sclerosis: from Clinical to Immunological DifferencesPMID 40423726Read ↗

The sex bias in systemic sclerosis: on the possible mechanisms underlying the female disease preponderance.Semantic proximity Read ↗

Sex bias in systemic lupus erythematosus: a molecular insightSemantic proximity Read ↗

Understanding Sex Differences in Autoimmune Diseases: Immunologic MechanismsSemantic proximity Read ↗

Sex-based differences in autoimmune diseases.Semantic proximity Read ↗

A Case of Double Standard: Sex Differences in Multiple Sclerosis Risk FactorsSemantic proximity Read ↗

The Immune System Is a Natural Target for Estrogen Action: Opposing Effects of Estrogen in Two Prototypical Autoimmune DiseasesSemantic proximity Read ↗

Sex Dimorphism in Pulmonary Arterial Hypertension Associated With Autoimmune Diseases.Semantic proximity Read ↗

Review: Male systemic lupus erythematosus: a review of sex disparities in this disease.Semantic proximity Read ↗

The molecular underpinnings of female predominance in lupus.Semantic proximity Read ↗

Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory GenesSemantic proximity Read ↗

Mechanisms underlying sex differences in autoimmunitySemantic proximity Read ↗

Sexual dimorphism in SLE: above and beyond sex hormonesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.