Article
Matrix Metalloproteinase and Aortic Aneurysm: A Two-sample Mendelian Randomization Study.
Annals of vascular surgery - 1 Aug 2024
Qin Tao, Zhong Jiankai, Li Pinglan, Liang Jianlin, Li Meijun, Zhang Guangjun
Abstract excerpt
BACKGROUND: Studies have linked matrix metalloproteinases (MMPs) to both thoracic aortic aneurysm and abdominal aortic aneurysm (TAA and AAA). The precise MMPs entailed in this procedure, however, were still unknown. This study used a two-sample Mendelian randomization (MR) analysis to look into the causal relationship between MMPs and the risk of TAA and AAA. METHODS: Eight MMPs, including MMP-1, MMP-2, MMP-3,...
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