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Serum fetuin-a and risk of thoracic aortic aneurysms: a two-sample mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Chen Yang, Zhu Jiayi, Guo Xin, Cao Chenghui, Xiao Xuan, Zhu Botao, Weng Shuwei, Hu Die, Luo Yonghong, Wang Shuai, Wu Sha, He Jia, Yang Yang, Peng Daoquan

Abstract excerpt

Background: Recent studies have revealed a significant decrease in serum fetuin-A levels in atherosclerotic aneurysms, indicating that fetuin-A may play a protective role in the progression of arterial calcification. However, the specific mechanism behind this phenomenon remains unclear. We aimed to examine the association between fetuin-A levels in thoracic aortic aneurysms (TAAs) and risk of TAAs and to...

Topics

Humans
alpha-2-HS-Glycoprotein
Mendelian Randomization Analysis
Aortic Aneurysm, Thoracic
Odds Ratio
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38469141
DOI: 10.3389/fendo.2024.1361416
PMCID: PMC10925661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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