Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis

Abstract excerpt

It has been presumed that rheumatoid arthritis (RA) joint pain is related to inflammation in the synovium; however, recent studies reveal that pain scores in patients do not correlate with synovial inflammation. We developed a machine-learning approach (graph-based gene expression module identification or GbGMI) to identify an 815-gene expression module associated with pain in synovial biopsy samples from...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytokine Signaling Pathways and Interactions
• Share to HER2/EGFR in Cancer Research
• Share to Rheumatoid Arthritis Research and Therapies