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Article

Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients

4 Jul 2018

Abstract excerpt

Joint pain causes significant morbidity in osteoarthritis (OA). The aetiology of joint pain in OA is not well understood. The synovial membrane as an innervated joint structure represents a potential source of peripheral pain in OA. Here we analyse, using a hypothesis-free next generation RNA sequencing, the differences in protein-coding and non-coding transcriptomes in knee synovial tissues from OA patients with...

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PMID: 29973527
DOI: 10.3390/genes9070338

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