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Article

Estimating biologically relevant parameters under uncertainty for experimental within-host murine West Nile virus infection

1 Apr 2016

Abstract excerpt

West Nile virus (WNV) is an emerging pathogen that has decimated bird populations and caused severe outbreaks of viral encephalitis in humans. Currently, little is known about the within-host viral kinetics of WNV during infection. We developed mathematical models to describe viral replication, spread and host immune response in wild-type and immunocompromised mice. Our approach fits a target cell-limited model...

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PMID: 27075003
DOI: 10.1098/rsif.2016.0130

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