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Article

Apolipoprotein E and Alzheimer's disease pathology in a diverse autopsy study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Nov 2025

Suemoto Claudia K, Paradela Regina, Leite Renata E P, Paes Vitor R, Pasqualucci Carlos A, Ferriolli Eduardo, Zatz Mayana, do Nascimento Santos Gabriel, de Alexandria Marvin Afonso Longo Salvador, Pereira Ana C, Fortea Juan, Naslavsky Michel, Grinberg Lea T

Abstract excerpt

INTRODUCTION: Apolipoprotein E allele 4 (APOE ε4) is the main genetic risk factor for late-onset Alzheimer's disease (AD), but most evidence comes from White populations in high-income countries. We investigated APOE and AD pathology in an ethnically diverse Brazilian autopsy cohort. METHODS: This cross-sectional study used Biobank for Aging Studies (BAS) data. AD pathology was evaluated with Braak, Consortium to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41268805
DOI: 10.1002/alz.70927
PMCID: PMC12635860

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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