Article
Climbing RAS, the everest of oncogenes.
Cancer discovery - 1 Jan 2014
Russo Mariangela, Di Nicolantonio Federica, Bardelli Alberto
Abstract excerpt
SUMMARY: Mutations that activate the small GTP-binding protein KRAS are the most common oncogenic event in human tumors. Thirty years after its discovery, mutant KRAS has yet to be therapeutically conquered.
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