Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Liquid biopsy of cerebrospinal fluid for MYD88 L265P mutation is useful for diagnosis of central nervous system lymphoma.

Cancer science - 1 Nov 2021

Yamagishi Yuki, Sasaki Nobuyoshi, Nakano Yoshiko, Matushita Yuko, Omura Takaki, Shimizu Saki, Saito Kuniaki, Kobayashi Keiichi, Narita Yoshitaka, Kondo Akihide, Shiokawa Yoshiaki, Nagane Motoo, Ichimura Koichi

Abstract excerpt

The current standard of diagnosing central nervous system (CNS) lymphoma is stereotactic biopsy, however the procedure has a risk of surgical complication. Liquid biopsy of the CSF is a less invasive, non-surgical method that can be used for diagnosing CNS lymphoma. In this study, we established a clinically applicable protocol for determining mutations in MYD88 in the CSF of patients with CNS lymphoma. CSF was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell-Free Nucleic Acids
Share to Central Nervous System Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to High-Throughput Nucleotide Sequencing

Share to Liquid Biopsy

Share to Lymphoma

Share to Myeloid Differentiation Factor 88

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 34523186
DOI: 10.1111/cas.15133
PMCID: PMC8586690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Liquid biopsy of cerebrospinal fluid for MYD88 L265P mutation is useful for diagnosis of central nervous system lymphoma.PMID 34523186Read ↗

High Detection Rate of MYD88 Mutations in Cerebrospinal Fluid From Patients With CNS LymphomasSemantic proximity Read ↗

Guiding treatment and clinical management of patients with CNS lymphomas by minimal-invasive detection of circulating tumor DNA in cerebrospinal fluidSemantic proximity Read ↗

The use of droplet digital PCR in liquid biopsies: A highly sensitive technique for MYD88 p.(L265P) detection in cerebrospinal fluid.Semantic proximity Read ↗

Reliable detection of CNS lymphoma-derived circulating tumor DNA in cerebrospinal fluid using multi-biomarker NGS profiling: insights from a real-world studySemantic proximity Read ↗

Rapid detection of the MYD88 L265P mutation for pre- and intra-operative diagnosis of primary central nervous system lymphoma.Semantic proximity Read ↗

Detection of circulating tumor DNA in plasma of patients with primary CNS lymphoma by digital droplet PCR.Semantic proximity Read ↗

A rapid genotyping panel for detection of primary central nervous system lymphoma.Semantic proximity Read ↗

Molecular diagnosis of primary CNS lymphoma in 2024 using MYD88Leu265Pro and IL-10.Semantic proximity Read ↗

Diagnostic approach to leptomeningeal involvement in diffuse large B-cell lymphoma.Semantic proximity Read ↗

Molecular analysis in liquid biopsies for diagnostics of primary central nervous system lymphoma: Review of literature and future opportunities.Semantic proximity Read ↗

Rapid tumor DNA analysis of cerebrospinal fluid accelerates treatment of central nervous system lymphoma.Semantic proximity Read ↗

Analysis of Driver Mutational Hot Spots in Blood-Derived Cell-Free DNA of Patients with Primary Central Nervous System Lymphoma Obtained before Intracerebral Biopsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.