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Article

Genetic determinants of plasma protein levels in the Estonian population.

Scientific reports - 2 Apr 2024

Kalnapenkis Anette, Jõeloo Maarja, Lepik Kaido, Kukuškina Viktorija, Kals Mart, Alasoo Kaur, Mägi Reedik, Esko Tõnu, Võsa Urmo

Abstract excerpt

The proteome holds great potential as an intermediate layer between the genome and phenome. Previous protein quantitative trait locus studies have focused mainly on describing the effects of common genetic variations on the proteome. Here, we assessed the impact of the common and rare genetic variations as well as the copy number variants (CNVs) on 326 plasma proteins measured in up to 500 individuals. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38565889
DOI: 10.1038/s41598-024-57966-3
PMCID: PMC10987560

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