Article
Investigating the shared genetic architecture between attention-deficit/hyperactivity disorder and risk taking behavior: A large-scale genomewide cross-trait analysis.
Journal of affective disorders - 1 Jul 2024
Chen Yanjing, Liu Ping, Yi Sijie, Fan Chunhua, Zhao Wei, Liu Jun
Abstract excerpt
BACKGROUND: This study aims to explore the genetic architecture shared between Attention-Deficit/Hyperactivity Disorder (ADHD) and risk behavior. METHODS: Based on the latest large-scale Genome-wide association studies (GWAS), we firstly employed Linkage disequilibrium score regression (LDSC) and Local Analysis of Variant Association (LAVA) to investigate the genetic correlation between risk behavior and ADHD....
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