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Article

Investigating the Bidirectional Association of Rheumatoid Arthritis and Thyroid Function: A Methodologic Assessment of Mendelian Randomization.

Arthritis care & research - 1 Aug 2024

Tan Yuxuan, Yao Huojie, Lin Chuhang, Lai Zhengtian, Li Haiying, Zhang Jing, Fu Yingyin, Wu Xiaomei, Yang Guang, Feng Liping, Jing Chunxia

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) and thyroid dysfunction are frequently observed in the same patient. However, whether they co-occur or exhibit a causal relationship remains uncertain. We aimed to systematically investigate the causal relationship between RA and thyroid function using a large sample and advanced methods. METHODS: Bidirectional two-sample Mendelian randomization (MR) analysis was performed...

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Identifiers

PMID: 38556923
DOI: 10.1002/acr.25335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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