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LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus

5 Jan 2024

Abstract excerpt

Crimean-Congo hemorrhagic fever virus (CCHFV) is the most widespread tick-born zoonotic bunyavirus that causes severe hemorrhagic fever and death in humans. CCHFV enters the cell via clathrin-mediated endocytosis which is dependent on its surface glycoproteins. However, the cellular receptors that are required for CCHFV entry are unknown. Here we show that the low density lipoprotein receptor (LDLR) is an entry...

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PMID: 38182887
DOI: 10.1038/s41422-023-00917-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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