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Quantification and molecular correlates of tertiary lymphoid structures in primary prostate cancer

27 Mar 2024

Abstract excerpt

OBJECTIVE: To morphologically describe tertiary lymphoid structures (TLS) in prostatectomy specimens and correlate them with clinical and transcriptomic features. METHODOLOGY: A total of 72 consecutive cases of entirely submitted radical prostatectomy (RP) patients tested with the Decipher Genomic Classifier were included in the study. Images were manually annotated using QuPath tools to denote tumor regions and...

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PMID: 38544351
DOI: 10.1002/pros.24684

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