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Article

Artificial oocyte activation: physiological, pathophysiological and ethical aspects

12 Sept 2018

Abstract excerpt

Infertile couples with low oocyte yield in combination with abnormal semen parameters may experience intra-cytoplasmic sperm injection (ICSI) failure. An established factor associated with ICSI failure is oocyte activation deficiency (AOD). The latter originates from seminal contributors, such as phospholipase C-zeta (PLCζ) that is not adequate to produce calcium (Ca2+) oscillations for oocyte activation. Apart...

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Identifiers

PMID: 30207496
DOI: 10.1080/19396368.2018.1516000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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