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Myeloid‑derived suppressor cell accumulation induces Treg expansion and modulates lung malignancy progression

21 Feb 2024

Abstract excerpt

Myeloid‑derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that suppress T cell immunity in tumor‑bearing hosts. The present study aimed to examine roles of T and MDSC subsets in lung malignancy. The study analyzed 102 cases with lung malignancy and 34 healthy individuals. Flow cytometry was performed for identification of T cell and MDSC subsets and their phenotypic characteristics in...

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PMID: 38533389
DOI: 10.3892/br.2024.1754

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