Article
Implications of MDSCs-targeting in lung cancer chemo-immunotherapeutics.
Pharmacological research - 1 Aug 2016
Adah Dickson, Hussain Muzammal, Qin Limei, Qin Li, Zhang Jiancun, Chen Xiaoping
Abstract excerpt
Despite advances in chemotherapy and immunotherapy, advanced lung cancer remains an incurable disease. Novel trends in anticancer therapeutics focus on harnessing the therapeutically-targeted tumor-related immune suppression. In this respect, myeloid-derived suppressor cells (MDSCs) have captured considerable attention in the last few years, as they are vividly implicated in tumor immune escape mechanisms. In...
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