Article
Enhanced circulating ILC2s and MDSCs may contribute to ensure maintenance of Th2 predominant in patients with lung cancer.
Molecular medicine reports - 1 Jun 2017
Wu Yumin, Yan Yulan, Su Zhaoliang, Bie Qingli, Chen Xiaobo, Barnie Prince Amoah, Guo Qi, Wang Shengjun, Xu Huaxi
Abstract excerpt
Group 2 innate lymphoid cells (ILC2s) were demonstrated to be involved in the initiation and coordination of type 2 T helper cell (Th2) responses. Myeloid‑derived suppressor cells (MDSCs) have received a great deal of attention for their role in creating an immunosuppressive microenvironment in cancer‑bearing hosts. However, the contributions of ILC2s in the occurrence and development of lung cancer, and the...
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