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Article

The Dual Role of the NFATc2/galectin-9 Axis in Modulating Tumor-Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 May 2024

Xiao Zhi-Jie, Wang Si-Qi, Chen Jun-Jiang, Li Yun, Jiang Yuchen, Tin Vicky Pui-Chi, Liu Jia, Hu Huiyi, Wong Maria Pik, Pan Yihang, Yam Judy Wai Ping

Abstract excerpt

Tumor-initiating cells (TICs) resilience and an immunosuppressive microenvironment are aggressive oncogenic phenotypes that contribute to unsatisfactory long-term outcomes in lung adenocarcinoma (LUAD) patients. The molecular mechanisms mediating the interaction between TICs and immune tolerance have not been elucidated. The role of Galectin-9 in oncogenesis and immunosuppressive microenvironment is still...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38528665
DOI: 10.1002/advs.202306059
PMCID: PMC11132051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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