Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CPSF4 promotes tumor-initiating phenotype by enhancing VEGF/NRP2/TAZ signaling in lung cancer.

Medical oncology (Northwood, London, England) - 26 Dec 2022

Song YingQiu, Sun Kai, Gong LiLan, Shi LinLi, Qin Tao, Wang ShuSen, Deng WuGuo, Chen WangBing, Zheng FeiMeng, Li GuiLing

Abstract excerpt

Lung cancer is the leading cause of malignant tumor-related deaths worldwide. The presence of tumor-initiating cells in lung cancer leads to tumor recurrence, metastasis, and resistance to conventional treatment. Cleavage and polyadenylation specificity factor 4 (CPSF4) activation in tumor cells contributes to the poor prognosis of lung cancer. However, the precise biological functions and molecular mechanisms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Lung Neoplasms

Share to Phenotype

Share to Signal Transduction

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 36567417
DOI: 10.1007/s12032-022-01919-1

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CPSF4 promotes tumor-initiating phenotype by enhancing VEGF/NRP2/TAZ signaling in lung cancer.PMID 36567417Read ↗

CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1Semantic proximity Read ↗

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma.Semantic proximity Read ↗

N-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc.Semantic proximity Read ↗

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinomaSemantic proximity Read ↗

NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fynSemantic proximity Read ↗

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4Semantic proximity Read ↗

Association Analysis of CPSF4-PRKDC Co-expression with Poor Prognosis, Immune Microenvironment Characteristics, and Sorafenib Sensitivity in Hepatocellular CarcinomaSemantic proximity Read ↗

CNBP controls tumor cell biology by regulating tumor‐promoting gene expressionSemantic proximity Read ↗

Characterization of a Cleavage Stimulation Factor, 3′ pre-RNA, Subunit 2, 64 kDa (CSTF2) as a Therapeutic Target for Lung CancerSemantic proximity Read ↗

NRP1-positive lung cancer cells possess tumor-initiating properties.Semantic proximity Read ↗

SSRP1 Promotes Lung Cancer Progression by Blocking the WNT Pathway and is Negatively Regulated by miRNA-28-5pSemantic proximity Read ↗

Impact of KIF4A on Cancer Stem Cells and EMT in Lung Cancer and GliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.