Article
Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells.
Oncology reports - 1 Jul 2017
Akashi Emiko, Fujihara Shintaro, Morishita Asahiro, Tadokoro Tomoko, Chiyo Taiga, Fujikawa Keiko, Kobara Hideki, Mori Hirohito, Iwama Hisakazu, Okano Keiichi, Suzuki Yasuyuki, Niki Toshiro, Hirashima Mitsuomi, Masaki Tsutomu
Abstract excerpt
The incidence of esophageal adenocarcinoma (EAC) is rapidly increasing in western countries. The overall mortality of this disease remains high with a 5-year survival rate of less than 20%, despite remarkable advances in the care of patients with EAC. Galectin-9 (Gal-9) is a tandem-repeat type galectin that exerts anti-proliferative effects on various cancer cell types. The aim of the present study was to...
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