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Article

Transcriptome free energy can serve as a dynamic patient-specific biomarker in acute myeloid leukemia.

NPJ systems biology and applications - 25 Mar 2024

Uechi Lisa, Vasudevan Swetha, Vilenski Daniela, Branciamore Sergio, Frankhouser David, O'Meally Denis, Meshinchi Soheil, Marcucci Guido, Kuo Ya-Huei, Rockne Russell, Kravchenko-Balasha Nataly

Abstract excerpt

Acute myeloid leukemia (AML) is prevalent in both adult and pediatric patients. Despite advances in patient categorization, the heterogeneity of AML remains a challenge. Recent studies have explored the use of gene expression data to enhance AML diagnosis and prognosis, however, alternative approaches rooted in physics and chemistry may provide another level of insight into AML transformation. Utilizing publicly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38527998
DOI: 10.1038/s41540-024-00352-6
PMCID: PMC10963775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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