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Article

Kinome expression profiling improves risk stratification and therapeutic targeting in myelodysplastic syndromes

25 Mar 2024

Abstract excerpt

ABSTRACT: The human kinome, which comprises >500 kinases, plays a critical role in regulating numerous essential cellular functions. Although the dysregulation of kinases has been observed in various human cancers, the characterization and clinical implications of kinase expressions in myelodysplastic syndromes (MDS) have not been systematically investigated. In this study, we evaluated the kinome expression...

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PMID: 38527292
DOI: 10.1182/bloodadvances.2023011512

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