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New developments in diagnosis, prognostication, and treatment of advanced systemic mastocytosis.

Blood - 16 Apr 2020

Reiter Andreas, George Tracy I, Gotlib Jason

Abstract excerpt

Systemic mastocytosis (SM) has greatly benefited from the broad application of precision medicine techniques to hematolymphoid neoplasms. Sensitive detection of the recurrent KIT D816V mutation and use of next-generation sequencing (NGS) panels to profile the genetic landscape of SM variants have been critical adjuncts to the diagnosis and subclassification of SM, and development of clinical-molecular prognostic...

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Identifiers

PMID: 32106312
DOI: 10.1182/blood.2019000932

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