Article
Rational Design of a Robust G-Quadruplex Aptamer as an Inhibitor to Alleviate Listeria monocytogenes Infection.
ACS applied materials & interfaces - 3 Apr 2024
Chen Xiaowan, Chang Yuting, Ye Mingyue, Wang Zhouping, Wu Shijia, Duan Nuo
Abstract excerpt
Listeria monocytogenes (LM) is one of the most invasive foodborne pathogens that cause listeriosis, making it imperative to explore novel inhibiting strategies for alleviating its infection. The adhesion and invasion of LM within host cells are partly orchestrated by an invasin protein internalin A (InlA), which facilitates bacterial passage by interacting with the host cell E-cadherin (E-Cad). Hence, in this...
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