Article
GAS5 rs2067079 and miR-137 rs1625579 functional SNPs and risk of chronic hepatitis B virus infection among Egyptian patients.
Scientific reports - 8 Oct 2021
Mahmoud Rania H, Hefzy Enas Mamdouh, Shaker Olfat G, Ahmed Tarek I, Abdelghaffar Noha K, Hassan Essam A, Ibrahim Amal A, Ali Doaa Y, Mohamed Mohamed M, Abdelaleem Omayma O
Abstract excerpt
Hepatitis B virus (HBV) infection is a significant health issue worldwide.. We attempted to fulfill the molecular mechanisms of epigenetic and genetic factors associated with chronic HBV (CHBV). Expression levels of the lncRNA growth arrest-specific 5 (GAS5) and miR-137 and their corresponding SNPs, rs2067079 (C/T) and rs1625579 (G/T) were analyzed in 117 CHBV patients and 120 controls to investigate the probable...
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