Article
Association of IRGM gene promoter polymorphisms with hepatitis B virus infection.
The journal of gene medicine - 1 Jul 2022
Sharma Ambika, Duseja Ajay, Parkash Jyoti, Changotra Harish
Abstract excerpt
BACKGROUND: In response to intracellular pathogens, the autophagy gene IRGM plays an essential role in the innate immune response. Various identified IRGM gene risk loci are associated with several diseases but, so far, no study is available that shows the association of IRGM with hepatitis B virus (HBV) infection. METHODS: We genotyped promoter variants (rs4958842, rs4958843, and rs4958846) of IRGM in HBV...
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