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Article

Effect of apolipoprotein E (APOE) gene polymorphisms on the lipid profile of children being treated for acute lymphoblastic leukemia.

International journal of hematology - 1 Jun 2024

Ioannidou Maria, Avgeros Chrysostomos, Georgiou Elisavet, Papadimitriou-Tsantarliotou Aliki, Dimitriadis Dimitrios, Tragiannidis Athanasios, Panagopoulou Paraskevi, Papakonstantinou Evgenia, Galli-Tsinopoulou Assimina, Makedou Kali, Hatzipantelis Emmanuel

Abstract excerpt

BACKGROUND: Medications used to treat acute lymphoblastic leukemia (ALL), such as L-asparaginase, can cause blood lipid disturbances. These can also be associated with polymorphisms of the lipoprotein lipase (LpL) and apolipoprotein E (APOE) genes. PROCEDURE: We aimed to investigate the association between lipid profile, certain LpL and APOE gene polymorphisms (rs268, rs328, rs1801177 and rs7412, rs429358...

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Share to Apolipoproteins E
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Share to Child, Preschool
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Share to Polymorphism, Genetic
Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

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Identifiers

PMID: 38507115
DOI: 10.1007/s12185-024-03748-6
PMCID: PMC11140815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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