Article
The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia.
BMC cancer - 2 Oct 2013
Künkele Annette, Grosse-Lordemann Anja, Schramm Alexander, Eggert Angelika, Schulte Johannes H, Bachmann Hagen S
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. While current treatment regimens achieve almost 80% overall survival, long-term side effects of chemotherapeutic agents can be severe. The functional BCL2-938C > A promoter polymorphism is known to influence the b...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
