Article
Polymorphism analysis of CTLA-4 in childhood acute lymphoblastic leukemia.
Pakistan journal of pharmaceutical sciences - 1 Jul 2014
Hui Liang, Lei Zhang, Peng Zeng, Ruobing Shan, Fenghua Zhang
Abstract excerpt
To investigate the correlation between cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism and children with acute lymphoblastic leukemia (ALL). A total of 86 children of ALL (23 HR, 54SR) and 112 healthy controls was selected. The genptypes were determined by means of polymerase chain reaction (PCR) and the PCR product sequencing. Genotype and alleles frequency of SNP-318, SNP+49 and SNP-CT60 were...
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