Article
An exploratory view into allelic drop-out of sequenced autosomal STRs.
Journal of forensic sciences - 1 May 2024
Foley Megan M, Koehler Gerwald, Fu Jun, Allen Robert, Wagner Jarrad R
Abstract excerpt
As massively parallel sequencing is implemented in forensic genetics, an understanding of sequence data must accompany these advancements, that is, accurate modeling of data for proper statistical analysis. Allelic drop-out, a common stochastic effect seen in genetic data, is often modeled in statistical analysis of STR results. This proof-of-concept study sequenced several serial dilutions of a standard sample...
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