Article
Maximizing allele detection: Effects of analytical threshold and DNA levels on rates of allele and locus drop-out.
Forensic science international. Genetics - 1 Dec 2012
Rakay Christine A, Bregu Joli, Grgicak Catherine M
Abstract excerpt
Interpretation of DNA evidence depends upon the ability of the analyst to accurately compare the DNA profile obtained from an item of evidence and the DNA profile of a standard. This interpretation becomes progressively more difficult as the number of 'drop-out' and 'drop-in' events increase. Analytical thresholds (AT) are typically selected to ensure the false detection of noise is minimized. However, there...
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