Article
Effect of multiple allelic drop-outs in forensic RMNE calculations.
Forensic science international. Genetics - 1 Nov 2015
Christophe Van Neste, Dieter Deforce, Filip Van Nieuwerburgh
Abstract excerpt
Technological advances such as massively parallel sequencing enable increasing amounts of genetic information to be obtained from increasingly challenging samples. Certainly on low template, degraded and multi-contributor samples, drop-outs will increase in number for many profiles simply by analyzing more loci, making it difficult to probabilistically assess how many drop-outs have occurred and at which loci...
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