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Article

High throughput AS LNA qPCR method for the detection of a specific mutation in poliovirus vaccine strains.

Vaccine - 2 Apr 2024

Opmeer Lizet, Gazzoli Isabella, Ballmann Mónika, Willemsen Marieke, Voshol Gerben P, Grudniewska-Lawton Magda, Havenga Menzo, Yallop Christopher, Hamidi Ahd, Gillissen Gert, Bakker Wilfried A M

Abstract excerpt

Sabin Inactivated Poliovirus Vaccine (sIPV) has become one of the preferred vaccination options for the last step in the Poliovirus eradication program. Sequencing of poliovirus samples is needed during the manufacturing of poliovirus vaccines to assure the safety and immunogenicity of these vaccines. Next-generation sequencing analysis is the current costly and time-consuming gold standard for monitoring the...

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Identifiers

PMID: 38503660
DOI: 10.1016/j.vaccine.2024.01.103
PMCID: PMC11007389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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