Article
High throughput AS LNA qPCR method for the detection of a specific mutation in poliovirus vaccine strains.
Vaccine - 2 Apr 2024
Opmeer Lizet, Gazzoli Isabella, Ballmann Mónika, Willemsen Marieke, Voshol Gerben P, Grudniewska-Lawton Magda, Havenga Menzo, Yallop Christopher, Hamidi Ahd, Gillissen Gert, Bakker Wilfried A M
Abstract excerpt
Sabin Inactivated Poliovirus Vaccine (sIPV) has become one of the preferred vaccination options for the last step in the Poliovirus eradication program. Sequencing of poliovirus samples is needed during the manufacturing of poliovirus vaccines to assure the safety and immunogenicity of these vacc...
Topics
- Humans
- Poliomyelitis
- Poliovirus Vaccine, Oral
- Poliovirus
- Poliovirus Vaccine, Inactivated
- Mutation
- Quality Control
- Oligonucleotides