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Establishment of an A/T-Rich Specifically MGB Probe digital droplet PCR Assays Based on SNP for Brucella wild strains and vaccine strains.

Diagnostic microbiology and infectious disease - 1 Sept 2024

Li Wanyang, Zhang Shuai, Dang Sheng, Gao Lanzhu, Li Guangchen, Cheng Dawei, Jiang Longguang, Huang Tianpeng, Zhai Jingbo

Abstract excerpt

In recent years, immunization with the S2 live-attenuated vaccine has been recognized as the most economical and effective strategy for preventing brucellosis in Inner Mongolia, China. However, there are still challenges related to vaccine toxicity and the inability to distinguish between vaccine immunization and natural infection. Therefore, in this study, we developed a digital droplet polymerase chain reaction...

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PMID: 39024932
DOI: 10.1016/j.diagmicrobio.2024.116432

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