Article
Diagnostic Assay Development for Poliovirus Eradication.
Journal of clinical microbiology - 1 Feb 2018
Gerloff Nancy, Sun Hong, Mandelbaum Mark, Maher Chelsea, Nix W Allan, Zaidi Sohail, Shaukat Shahzad, Seakamela Lerato, Nalavade Uma P, Sharma Deepa K, Oberste M Steven, Vega Everardo
Abstract excerpt
With poliovirus eradication nearing, few pockets of active wild poliovirus (WPV) transmission remain in the world. Intratypic differentiation (ITD) plays a crucial part in laboratory surveillance as the molecular detection method that can identify and distinguish wild and vaccine-like polioviruses isolated from acute flaccid paralysis cases or environmental sources. The need to detect new variants of WPV serotype...
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