Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1

9 Mar 2017

Abstract excerpt

Skin aging is a complicated physiological process and epigenetic feature, including microRNA-mediated regulation and DNA methylation, have been shown to contribute to this process. DNA methylation is regulated by DNA methyltransferase, of which DNA methyltransferase 1 (DNMT1) is the most abundantly known. But evidence supporting its role in skin aging remains scarce, and no report regards its specifical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Skin Protection and Aging
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28277545
DOI: 10.1038/cddis.2017.75

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1PMID 28277545Read ↗

Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1Semantic proximity Read ↗

The Role of microRNAs in Organismal and Skin AgingSemantic proximity Read ↗

The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence.Semantic proximity Read ↗

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblastsSemantic proximity Read ↗

Diagnostic biomarkers for skin agingSemantic proximity Read ↗

Biomarkers of UVB radiation-related senescent fibroblastsSemantic proximity Read ↗

Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapiesSemantic proximity Read ↗

Skin Rejuvenation by Modulation of DNA MethylationSemantic proximity Read ↗

Identification of senescence-inducing microRNAs in normal human keratinocytesSemantic proximity Read ↗

UV irradiation‐induced DNA hypomethylation around WNT1 gene: Implications for solar lentiginesSemantic proximity Read ↗

The effect of aging in primary human dermal fibroblastsSemantic proximity Read ↗

Aging is associated with highly defined epigenetic changes in the human epidermisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.