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Article

Caspase-8 polymorphisms and risk of gallbladder cancer in a northern Indian population.

Molecular carcinogenesis - 1 Jul 2010

Srivastava Kshitij, Srivastava Anvesha, Mittal Balraj

Abstract excerpt

Caspase-8 (CASP8) is a key controller of apoptosis, and its deregulation plays an important role in carcinogenesis. To evaluate the role of CASP8 polymorphisms in gallbladder cancer (GBC), we examined the risk associated with three single-nucleotide polymorphisms (SNPs) in a case-control study in North Indian population. Genotypes and haplotypes of the CASP8 polymorphisms (-652 6N ins/del; rs3834129, Ex13 + 51G >...

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Identifiers

PMID: 20564345
DOI: 10.1002/mc.20641

Genes

CASP8

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