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Article

Do TNFA -308 G/A and IL6 -174 G/C gene polymorphisms modulate risk of gallbladder cancer in the north Indian population?

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000

Vishnoi Monika, Pandey Sachchida Nand, Choudhury Gourdas, Kumar Ashok, Modi Dinesh Raj, Mittal Balraj

Abstract excerpt

OBJECTIVES: Gallbladder carcinoma (GBC) is highly aggressive neoplasm which arises in the background of gall stones and inflammation. GBC affects women 2-3 times more frequently than men. Pro-inflammatory TNFA and IL6 gene polymorphism has been associated with various inflammatory diseases. The aim of this study was to investigate whether TNFA -308 (G/A) and IL6 -174 G/C polymorphisms within flanking region of...

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PMID: 18260730

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