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DUSP22 Ameliorates Endothelial‐to‐Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways

1 Jan 2024

Abstract excerpt

Endothelial‐to‐mesenchymal transition (EndMT) is the process by which endothelial cells lose their endothelial properties and acquire mesenchymal characteristics. Dual‐specific protein phosphatase 22 (DUSP22) inactivates various protein kinases and transcription factors by dephosphorylating serine/threonine residues: hence, it plays a key role in many diseases. The aim of this study was to explore the functional...

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PMID: 38495810
DOI: 10.1155/2024/5583961

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