Article
Unraveling novel mutation patterns and morphological variations in two dalbavancin-resistant MRSA strains in Austria using whole genome sequencing and transmission electron microscopy.
BMC infectious diseases - 2 Sept 2024
Hotz Julian Frederic, Staudacher Moritz, Schefberger Katharina, Spettel Kathrin, Schmid Katharina, Kriz Richard, Schneider Lisa, Hagemann Jürgen Benjamin, Cyran Norbert, Schmidt Katy, Starzengruber Peter, Lötsch Felix, Leutzendorff Amelie, Daller Simon, Ramharter Michael, Burgmann Heinz, Lagler Heimo
Abstract excerpt
BACKGROUND: The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains resistant to non-beta-lactam antimicrobials poses a significant challenge in treating severe MRSA bloodstream infections. This study explores resistance development and mechanisms in MRSA isolates, especially after the first dalbavancin-resistant MRSA strain in our hospital in 2016. METHODS: This study investigated...
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