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Cytogenetics of Pediatric Acute Myeloid Leukemia: A Review of the Current Knowledge

17 Jun 2021

Abstract excerpt

Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to morphology, immunophenotyping, germline and somatic cytogenetic and genetic abnormalities. Over recent decades, outcomes have greatly improved, although survival rates remain around 70% and the relapse rate is high, at around 30%. Cytogenetics is an important factor for diagnosis and indication of prognosis. The main cytogenetic...

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PMID: 34204358
DOI: 10.3390/genes12060924

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