Article
Novel signals and polygenic score for height are associated with pubertal growth traits in Southwestern American Indians.
Human molecular genetics - 18 May 2024
Ramírez-Luzuriaga Maria J, Kobes Sayuko, Hsueh Wen-Chi, Baier Leslie J, Hanson Robert L
Abstract excerpt
Most genetic variants associated with adult height have been identified through large genome-wide association studies (GWASs) in European-ancestry cohorts. However, it is unclear how these variants influence linear growth during adolescence. This study uses anthropometric and genotypic data from a longitudinal study conducted in an American Indian community in Arizona between 1965-2007. Growth parameters (i.e....
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